Reverse transcription

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Reverse transcription is an exception to Crick's central dogma whereby the information in RNA is transferred into DNA by an independent DNA polymerase, reverse transcriptase. It is the opposite of transcription. Reverse transcription is a process used by RNA retroviruses, such as HIV, to "paste" themselves into their host's (e.g. human) genome. Reverse transcription is also used by transposons, "parasitic" DNA which copies itself to RNA and then inserts copies of itself back into the chromosome.

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